Fans of the Premier League are in for a midweek treat on Wednesday with the ‘Big Six’ all in action on the same night.
Leaders Liverpool will be aiming to maintain their place at the top of the standings when they welcome Watford to Anfield.
The Reds head into the game just one point in front of Manchester City and they will be hoping to produce a better performance than has been the case in recent weeks.
Watford remain comfortably positioned in the top half of the table and will fancy their chances of derailing Liverpool’s title bid.
The Hornets smashed five past Cardiff City in their last away match and punters could be tempted to use this Betfred sign-up offer to back them at odds of 10/1 to record another victory.
Elsewhere on Wednesday, Man City are big favourites to beat improving West Ham United at the Etihad Stadium.
City have won their last six meetings with the Hammers in all competitions and they are strongly fancied to make it seven in a row.
The game of the night is at Stamford Bridge, as Chelsea take on Tottenham Hotspur. The Blues are sixth in the table, three points behind fourth-placed Arsenal with a game in hand.
Spurs are currently third, six points adrift of Liverpool following their shock defeat at Burnley over the weekend.
Chelsea were beaten 3-1 in the reverse fixture – Dele Alli, Harry Kane and Son Heung-min were on target for Spurs.
The two sides also met in the Carabao Cup semi-finals, with Chelsea progressing after a penalty shoot-out.
They were beaten on penalties in Sunday’s final against Man City and will be eager to bounce back against their London rivals.
Arsenal will bid to strengthen their grip on fourth place when they welcome Bournemouth to the Emirates Stadium.
The Gunners triumphed 2-1 when the two sides last met at the Vitality Stadium during November and they look a good bet to complete the double back on home soil.
Ole Gunnar Solskjaer is yet to lose in the Premier League since taking over as Manchester United’s temporary manager, but that record could come under threat at Crystal Palace.
United currently have around 10 players unavailable for selection and Palace are the sort of team who could take advantage.
They extended their unbeaten run to six matches in all competitions with a 4-1 victory at Leicester City over the weekend and may pick up at least a point against the Red Devils at Selhurst Park.