| Score | 5-2 to Brighton and Hove Albion |
| Referee | Sunny Singh Gill |
| Competition | FA Cup 4th round |
| Venue | Bramall Lane |
| Attendance | 18,391 |
View Sheffield United v Brighton and Hove Albion head to head
Manager: Chris Wilder
| Gustavo Hamer | 44 |
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| Will Osula | 45+8 |
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| Yasser Larouci for Rhys Norrington-Davies | 56 |
| James McAtee for Ben Brereton Diaz | 63 |
| Ollie McBurnie for Will Osula | 63 |
| Andre Brooks for Ben Osborn | 64 |
| Vinícius Souza for Gustavo Hamer | 76 |
| Oliver Norwood | 10 | Y |
| Gustavo Hamer | 45+7 | Y |
Manager: Roberto De Zerbi
| Facundo Buonanotte | 14 |
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| João Pedro | penalty | 29 |
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| João Pedro | penalty | 52 |
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| João Pedro | 67 |
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| Danny Welbeck | 90+7 |
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| Lewis Dunk for Igor Julio | 62 |
| Danny Welbeck for Evan Ferguson | 62 |
| Adam Lallana for Facundo Buonanotte | 72 |
| Tariq Lamptey for Jack Hinshelwood | 72 |
| Carlos Baleba for Billy Gilmour | 84 |
| Adam Webster | 55 | Y |