The table below shows New Brighton Tower's overall record against each of their former football league opponents.
| Opposition | P | W | D | L | F | A |
|---|---|---|---|---|---|---|
| Barnsley | 6 | 3 | 2 | 1 | 13 | 7 |
| Blackpool | 4 | 3 | 1 | 0 | 8 | 2 |
| Bolton Wanderers | 2 | 1 | 0 | 1 | 4 | 3 |
| Burnley | 2 | 1 | 0 | 1 | 3 | 3 |
| Burslem Port Vale | 2 | 1 | 1 | 0 | 1 | 0 |
| Burton Swifts | 6 | 2 | 3 | 1 | 13 | 7 |
| Chesterfield Town | 4 | 1 | 1 | 2 | 6 | 9 |
| Darwen | 2 | 2 | 0 | 0 | 11 | 2 |
| Gainsborough Trinity | 6 | 3 | 1 | 2 | 14 | 12 |
| Glossop North End | 4 | 2 | 1 | 1 | 4 | 7 |
| Grimsby Town | 6 | 4 | 1 | 1 | 15 | 9 |
| Leicester City | 4 | 1 | 3 | 0 | 5 | 4 |
| Leicester Fosse | 2 | 1 | 0 | 1 | 2 | 4 |
| Lincoln City | 6 | 4 | 1 | 1 | 11 | 4 |
| Loughborough | 4 | 3 | 0 | 1 | 8 | 7 |
| Luton Town | 4 | 4 | 0 | 0 | 16 | 4 |
| Manchester City | 2 | 0 | 1 | 1 | 1 | 2 |
| Manchester United | 4 | 1 | 0 | 3 | 4 | 7 |
| Middlesbrough | 4 | 1 | 1 | 2 | 7 | 9 |
| Newton Heath | 2 | 1 | 0 | 1 | 2 | 4 |
| Port Vale | 4 | 2 | 2 | 0 | 7 | 3 |
| Sheffield Wednesday | 2 | 0 | 1 | 1 | 2 | 6 |
| Small Heath | 6 | 1 | 2 | 3 | 8 | 11 |
| Stockport County | 2 | 2 | 0 | 0 | 8 | 0 |
| Walsall | 6 | 2 | 2 | 2 | 16 | 8 |
| West Bromwich Albion | 1 | 0 | 0 | 1 | 0 | 2 |
| Wolverhampton Wanderers | 1 | 0 | 0 | 1 | 1 | 5 |
| Woolwich Arsenal | 6 | 2 | 0 | 4 | 5 | 14 |