The table below shows Morecambe's overall record against each of their former football league opponents.
| Opposition | P | W | D | L | F | A |
|---|---|---|---|---|---|---|
| Accrington Stanley | 32 | 6 | 9 | 17 | 39 | 54 |
| AFC Bournemouth | 5 | 1 | 1 | 3 | 6 | 7 |
| AFC Wimbledon | 16 | 6 | 5 | 5 | 26 | 21 |
| Aldershot Town | 10 | 5 | 2 | 3 | 12 | 9 |
| Bangor City | 1 | 1 | 0 | 0 | 3 | 2 |
| Barnet | 18 | 7 | 5 | 6 | 24 | 22 |
| Barnsley | 4 | 2 | 0 | 2 | 6 | 9 |
| Barrow | 7 | 5 | 1 | 1 | 11 | 6 |
| Bishop Auckland | 1 | 0 | 0 | 1 | 0 | 5 |
| Blackburn Rovers | 1 | 1 | 0 | 0 | 2 | 1 |
| Blackpool | 6 | 2 | 0 | 4 | 8 | 16 |
| Blyth Spartans | 2 | 0 | 0 | 2 | 2 | 4 |
| Bolton Wanderers | 6 | 0 | 4 | 2 | 3 | 5 |
| Boston United | 1 | 0 | 0 | 1 | 0 | 3 |
| Bradford City | 24 | 7 | 6 | 11 | 23 | 29 |
| Brentford | 5 | 3 | 0 | 2 | 7 | 5 |
| Bristol Rovers | 10 | 3 | 2 | 5 | 20 | 17 |
| Bromley | 2 | 0 | 0 | 2 | 0 | 3 |
| Burnley | 1 | 0 | 0 | 1 | 1 | 3 |
| Burton Albion | 17 | 6 | 3 | 8 | 30 | 30 |
| Bury | 18 | 7 | 3 | 8 | 22 | 24 |
| Buxton | 1 | 1 | 0 | 0 | 1 | 0 |
| Cambridge United | 19 | 6 | 4 | 9 | 20 | 33 |
| Carlisle United | 25 | 5 | 9 | 11 | 28 | 38 |
| Charlton Athletic | 4 | 2 | 1 | 1 | 9 | 10 |
| Chelsea | 2 | 0 | 0 | 2 | 0 | 9 |
| Cheltenham Town | 30 | 9 | 7 | 14 | 31 | 41 |
| Chester | 1 | 1 | 0 | 0 | 1 | 0 |
| Chester City | 6 | 5 | 1 | 0 | 15 | 8 |
| Chesterfield | 17 | 6 | 7 | 4 | 27 | 26 |
| Colchester United | 14 | 4 | 7 | 3 | 16 | 12 |
| Coventry City | 6 | 2 | 2 | 2 | 7 | 5 |
| Crawley Town | 15 | 7 | 4 | 4 | 25 | 18 |
| Crewe Alexandra | 20 | 5 | 3 | 12 | 21 | 36 |
| Dagenham and Redbridge | 20 | 9 | 4 | 7 | 27 | 29 |
| Darlington | 6 | 3 | 2 | 1 | 9 | 5 |
| Derby County | 2 | 0 | 1 | 1 | 1 | 6 |
| Doncaster Rovers | 8 | 2 | 1 | 5 | 11 | 15 |
| Dover Athletic | 1 | 0 | 0 | 1 | 0 | 1 |
| Emley | 2 | 0 | 2 | 0 | 4 | 4 |
| Everton Academy | 2 | 0 | 1 | 1 | 3 | 4 |
| Exeter City | 21 | 4 | 9 | 8 | 25 | 34 |
| FC Halifax Town | 2 | 0 | 1 | 1 | 0 | 1 |
| Fleetwood Town | 13 | 4 | 4 | 5 | 16 | 19 |
| Forest Green Rovers | 12 | 5 | 3 | 4 | 17 | 14 |
| Gillingham | 14 | 1 | 4 | 9 | 11 | 24 |
| Grimsby Town | 25 | 8 | 9 | 8 | 29 | 33 |
| Harrogate Town | 7 | 3 | 1 | 3 | 8 | 9 |
| Hartlepool United | 12 | 2 | 4 | 6 | 15 | 19 |
| Hereford United | 8 | 3 | 2 | 3 | 11 | 9 |
| Huddersfield Town | 2 | 0 | 0 | 2 | 0 | 6 |
| Hull City | 2 | 0 | 0 | 2 | 2 | 4 |
| Ipswich Town | 6 | 0 | 2 | 4 | 4 | 16 |
| Kidderminster Harriers | 1 | 1 | 0 | 0 | 2 | 1 |
| Leicester City | 1 | 0 | 1 | 0 | 2 | 2 |
| Leyton Orient | 7 | 3 | 0 | 4 | 5 | 7 |
| Lincoln City | 21 | 5 | 6 | 10 | 25 | 30 |
| Liverpool Academy | 1 | 0 | 0 | 1 | 0 | 3 |
| Luton Town | 10 | 2 | 2 | 6 | 10 | 15 |
| Macclesfield Town | 15 | 7 | 4 | 4 | 20 | 15 |
| Maldon and Tiptree | 1 | 1 | 0 | 0 | 1 | 0 |
| Manchester United | 1 | 1 | 0 | 0 | 4 | 0 |
| Mansfield Town | 21 | 5 | 5 | 11 | 22 | 33 |
| Millwall | 1 | 0 | 0 | 1 | 0 | 2 |
| Milton Keynes Dons | 13 | 2 | 1 | 10 | 10 | 28 |
| Newcastle United | 2 | 0 | 0 | 2 | 0 | 9 |
| Newport County | 22 | 9 | 4 | 9 | 31 | 31 |
| Northampton Town | 18 | 2 | 6 | 10 | 20 | 35 |
| Northwich Victoria | 1 | 0 | 0 | 1 | 1 | 3 |
| Nottingham Forest | 1 | 0 | 0 | 1 | 0 | 4 |
| Nottingham Forest Academy | 1 | 1 | 0 | 0 | 4 | 2 |
| Notts County | 18 | 5 | 7 | 6 | 21 | 28 |
| Oldham Athletic | 8 | 4 | 1 | 3 | 13 | 14 |
| Oxford United | 17 | 3 | 8 | 6 | 16 | 28 |
| Peterborough United | 4 | 1 | 1 | 2 | 4 | 9 |
| Plymouth Argyle | 17 | 3 | 4 | 10 | 16 | 33 |
| Port Vale | 24 | 9 | 5 | 10 | 24 | 30 |
| Portsmouth | 12 | 2 | 7 | 3 | 14 | 18 |
| Preston North End | 6 | 1 | 1 | 4 | 10 | 19 |
| Rochdale | 14 | 4 | 5 | 5 | 18 | 19 |
| Rotherham United | 19 | 6 | 5 | 8 | 28 | 30 |
| Salford City | 8 | 2 | 1 | 5 | 8 | 14 |
| Scarborough | 1 | 0 | 0 | 1 | 0 | 2 |
| Scunthorpe United | 6 | 1 | 3 | 2 | 7 | 9 |
| Sheffield United | 2 | 0 | 0 | 2 | 0 | 6 |
| Sheffield Wednesday | 6 | 1 | 0 | 5 | 2 | 12 |
| Shrewsbury Town | 18 | 5 | 4 | 9 | 14 | 28 |
| Solihull Moors | 1 | 1 | 0 | 0 | 4 | 2 |
| South Liverpool | 1 | 0 | 0 | 1 | 0 | 1 |
| South Shields | 1 | 1 | 0 | 0 | 2 | 1 |
| Southend United | 13 | 10 | 2 | 1 | 21 | 12 |
| Stevenage | 15 | 1 | 6 | 8 | 12 | 23 |
| Stockport County | 7 | 3 | 1 | 3 | 12 | 10 |
| Stoke City | 3 | 1 | 1 | 1 | 4 | 3 |
| Sunderland | 4 | 0 | 0 | 4 | 0 | 9 |
| Sutton United | 2 | 2 | 0 | 0 | 4 | 2 |
| Swansea City | 1 | 0 | 0 | 1 | 0 | 2 |
| Swindon Town | 12 | 2 | 3 | 7 | 11 | 22 |
| Torquay United | 10 | 2 | 4 | 4 | 11 | 14 |
| Tottenham Hotspur | 1 | 0 | 0 | 1 | 1 | 3 |
| Tranmere Rovers | 14 | 6 | 3 | 5 | 18 | 17 |
| Walsall | 9 | 4 | 1 | 4 | 9 | 9 |
| Weymouth | 1 | 0 | 0 | 1 | 0 | 1 |
| Wigan Athletic | 3 | 1 | 0 | 2 | 4 | 7 |
| Wolverhampton Wanderers | 3 | 2 | 1 | 0 | 6 | 3 |
| Worthing | 1 | 1 | 0 | 0 | 2 | 0 |
| Wrexham | 5 | 0 | 1 | 4 | 5 | 17 |
| Wycombe Wanderers | 23 | 7 | 6 | 10 | 25 | 31 |
| Yeovil Town | 8 | 5 | 1 | 2 | 18 | 15 |
| York City | 14 | 1 | 7 | 6 | 11 | 16 |