The table below shows Fulham's overall record against each of their Premier League opponents.
| Opposition | P | W | D | L | F | A |
|---|---|---|---|---|---|---|
| AFC Bournemouth | 10 | 2 | 2 | 6 | 10 | 18 |
| Arsenal | 38 | 4 | 8 | 26 | 29 | 81 |
| Aston Villa | 36 | 8 | 11 | 17 | 34 | 52 |
| Birmingham City | 14 | 4 | 6 | 4 | 14 | 12 |
| Blackburn Rovers | 22 | 6 | 5 | 11 | 28 | 37 |
| Blackpool | 2 | 1 | 1 | 0 | 5 | 2 |
| Bolton Wanderers | 22 | 12 | 7 | 3 | 35 | 15 |
| Brentford | 8 | 4 | 2 | 2 | 13 | 12 |
| Brighton and Hove Albion | 12 | 6 | 5 | 1 | 20 | 11 |
| Burnley | 10 | 4 | 3 | 3 | 18 | 15 |
| Cardiff City | 4 | 1 | 0 | 3 | 5 | 9 |
| Charlton Athletic | 12 | 5 | 5 | 2 | 14 | 11 |
| Chelsea | 38 | 4 | 11 | 23 | 28 | 61 |
| Crystal Palace | 16 | 4 | 6 | 6 | 20 | 20 |
| Derby County | 4 | 1 | 3 | 0 | 3 | 2 |
| Everton | 38 | 12 | 5 | 21 | 37 | 59 |
| Huddersfield Town | 2 | 1 | 0 | 1 | 1 | 1 |
| Hull City | 6 | 1 | 1 | 4 | 5 | 13 |
| Ipswich Town | 4 | 0 | 3 | 1 | 4 | 5 |
| Leeds United | 12 | 6 | 1 | 5 | 16 | 15 |
| Leicester City | 12 | 7 | 3 | 2 | 18 | 11 |
| Liverpool | 38 | 8 | 8 | 22 | 37 | 73 |
| Luton Town | 2 | 2 | 0 | 0 | 5 | 2 |
| Manchester City | 36 | 4 | 9 | 23 | 40 | 87 |
| Manchester United | 38 | 4 | 7 | 27 | 38 | 80 |
| Middlesbrough | 16 | 6 | 3 | 7 | 21 | 22 |
| Newcastle United | 36 | 15 | 5 | 16 | 43 | 49 |
| Norwich City | 8 | 6 | 2 | 0 | 18 | 3 |
| Nottingham Forest | 8 | 6 | 1 | 1 | 15 | 6 |
| Portsmouth | 14 | 6 | 4 | 4 | 19 | 16 |
| Queens Park Rangers | 4 | 3 | 0 | 1 | 11 | 4 |
| Reading | 6 | 2 | 1 | 3 | 10 | 10 |
| Sheffield United | 6 | 3 | 2 | 1 | 9 | 7 |
| Southampton | 20 | 7 | 8 | 5 | 26 | 28 |
| Stoke City | 12 | 6 | 1 | 5 | 12 | 12 |
| Sunderland | 22 | 10 | 7 | 5 | 27 | 20 |
| Swansea City | 6 | 1 | 0 | 5 | 5 | 11 |
| Tottenham Hotspur | 38 | 11 | 8 | 19 | 38 | 56 |
| Watford | 4 | 0 | 3 | 1 | 5 | 8 |
| West Bromwich Albion | 18 | 8 | 7 | 3 | 29 | 12 |
| West Ham United | 32 | 7 | 7 | 18 | 36 | 49 |
| Wigan Athletic | 16 | 7 | 7 | 2 | 18 | 10 |
| Wolverhampton Wanderers | 20 | 5 | 7 | 8 | 23 | 23 |