Omit day and month for end of season table.
| Pos | Team | Pld | W | D | L | GF | GA | GD | Pts |
|---|---|---|---|---|---|---|---|---|---|
| Fulham | 44 | 26 | 9 | 9 | 99 | 39 | 60 | 87 | |
| AFC Bournemouth | 44 | 23 | 13 | 8 | 72 | 39 | 33 | 82 | |
| Nottingham Forest | 44 | 23 | 10 | 11 | 72 | 38 | 34 | 79 | |
| Huddersfield Town | 45 | 22 | 13 | 10 | 62 | 47 | 15 | 79 | |
| Luton Town | 44 | 20 | 12 | 12 | 62 | 48 | 14 | 72 | |
| Sheffield United | 45 | 20 | 12 | 13 | 59 | 45 | 14 | 72 | |
| Middlesbrough | 45 | 20 | 10 | 15 | 58 | 46 | 12 | 70 | |
| Millwall | 45 | 18 | 15 | 12 | 53 | 44 | 9 | 69 | |
| Blackburn Rovers | 45 | 18 | 12 | 15 | 57 | 49 | 8 | 66 | |
| West Bromwich Albion | 45 | 17 | 13 | 15 | 48 | 45 | 3 | 64 | |
| Coventry City | 45 | 17 | 12 | 16 | 59 | 58 | 1 | 63 | |
| Queens Park Rangers | 45 | 18 | 9 | 18 | 59 | 59 | 0 | 63 | |
| Stoke City | 45 | 17 | 10 | 18 | 56 | 51 | 5 | 61 | |
| Preston North End | 45 | 15 | 16 | 14 | 48 | 55 | -7 | 61 | |
| Swansea City | 45 | 16 | 13 | 16 | 58 | 67 | -9 | 61 | |
| Blackpool | 45 | 16 | 12 | 17 | 54 | 53 | 1 | 60 | |
| Bristol City | 45 | 15 | 10 | 20 | 62 | 75 | -13 | 55 | |
| Hull City | 45 | 14 | 8 | 23 | 40 | 53 | -13 | 50 | |
| Cardiff City | 45 | 14 | 8 | 23 | 49 | 68 | -19 | 50 | |
| Birmingham City | 45 | 11 | 14 | 20 | 49 | 73 | -24 | 47 | |
| Reading | 45 | 13 | 8 | 24 | 54 | 86 | -32 | 41 | |
| Derby County | 45 | 14 | 13 | 18 | 45 | 52 | -7 | 34 | |
| Peterborough United | 45 | 8 | 10 | 27 | 38 | 87 | -49 | 34 | |
| Barnsley | 45 | 6 | 12 | 27 | 33 | 69 | -36 | 30 |
| 22 Sep 2021 | Derby County were subjected to a 12 point Sporting Sanction by the Football League with effect from 22 September 2021 due to entering Administration. | |
| 16 Nov 2021 | Derby County were subjected to a nine point Sporting Sanction by the Football League with effect from 16 November 2021 due to breaching the EFL Profitability and Sustainability (P&S) rules. | |
| 17 Nov 2021 | Reading were subjected to a six point Sporting Sanction by the Football League with effect from 17 November 2021 due to breaching the EFL Profitability and Sustainability (P&S) rules. |