Omit day and month for end of season table.
| Pos | Team | Pld | W | D | L | GF | GA | GD | Pts |
|---|---|---|---|---|---|---|---|---|---|
| Forest Green Rovers | 46 | 23 | 15 | 8 | 75 | 44 | 31 | 84 | |
| Exeter City | 46 | 23 | 15 | 8 | 65 | 41 | 24 | 84 | |
| Bristol Rovers | 46 | 23 | 11 | 12 | 71 | 49 | 22 | 80 | |
| Northampton Town | 46 | 23 | 11 | 12 | 60 | 38 | 22 | 80 | |
| Port Vale | 46 | 22 | 12 | 12 | 67 | 46 | 21 | 78 | |
| Swindon Town | 46 | 22 | 11 | 13 | 77 | 54 | 23 | 77 | |
| Mansfield Town | 46 | 22 | 11 | 13 | 67 | 52 | 15 | 77 | |
| Sutton United | 46 | 22 | 10 | 14 | 69 | 53 | 16 | 76 | |
| Tranmere Rovers | 46 | 21 | 12 | 13 | 53 | 40 | 13 | 75 | |
| Salford City | 46 | 19 | 13 | 14 | 60 | 46 | 14 | 70 | |
| Newport County | 46 | 19 | 12 | 15 | 67 | 58 | 9 | 69 | |
| Crawley Town | 46 | 17 | 10 | 19 | 56 | 66 | -10 | 61 | |
| Leyton Orient | 46 | 14 | 16 | 16 | 62 | 47 | 15 | 58 | |
| Bradford City | 46 | 14 | 16 | 16 | 53 | 55 | -2 | 58 | |
| Colchester United | 46 | 14 | 13 | 19 | 48 | 60 | -12 | 55 | |
| Walsall | 46 | 14 | 12 | 20 | 47 | 60 | -13 | 54 | |
| Hartlepool United | 46 | 14 | 12 | 20 | 44 | 64 | -20 | 54 | |
| Rochdale | 46 | 12 | 17 | 17 | 51 | 59 | -8 | 53 | |
| Harrogate Town | 46 | 14 | 11 | 21 | 64 | 75 | -11 | 53 | |
| Carlisle United | 46 | 14 | 11 | 21 | 39 | 62 | -23 | 53 | |
| Stevenage | 46 | 11 | 14 | 21 | 45 | 68 | -23 | 47 | |
| Barrow | 46 | 10 | 14 | 22 | 44 | 57 | -13 | 44 | |
| Oldham Athletic | 46 | 9 | 11 | 26 | 46 | 75 | -29 | 38 | |
| Scunthorpe United | 46 | 4 | 14 | 28 | 29 | 90 | -61 | 26 |
| 14 May 2022 | Mansfield Town 2-1 Northampton Town | |
| 15 May 2022 | Swindon Town 2-1 Port Vale | |
| 18 May 2022 | Northampton Town 0-1 Mansfield Town | |
| 19 May 2022 | Port Vale 1-0 Swindon Town | |
| 28 May 2022 | Mansfield Town 0-3 Port Vale |