| Score | 4-1 to Leyton Orient |
| Referee | Dean Whitestone |
| Competition | League One |
| Venue | Home Park |
| Attendance | 11,501 |
View Plymouth Argyle v Leyton Orient head to head
| Yannick Bolasie | 63 |
|
| Kári Arnason for Rory Patterson | 72 |
| David Button for Luke Young | 77 |
| Romain Larrieu | 75 | R |
| Stephane Zubar | 90 | Y |
| Scott McGleish | penalty | 13 |
|
| Dean Cox | 15 |
|
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| Alex Revell | 77 |
|
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| Alex Revell | 89 |
|
| Ben Chorley for Matthew Spring | 67 |
| Alex Revell for Scott McGleish | 67 |
| Adam Chambers for Tom Carroll | 80 |
| Stephen Dawson | 71 | Y |
| Adam Barrett | 86 | Y |
Comments:
FINAL LEAGUE POSITION 2010-11: 23rd Plymouth Argyle named only five of a possible seven substitutes.Comments:
FINAL LEAGUE POSITION 2010-11: 7th