| Score | 4-0 to Nigeria |
| Referee | Gehad Grisha |
| Competition | FIFA World Cup Africa group B |
| Venue | Godswill Akpabio International Stadium, Uyo |
| Attendance | 27,000 |
View Nigeria v Cameroon head to head
Manager: Gernot Rohr
| Odion Ighalo | 29 |
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| John Obi Mikel | 43 |
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| Victor Moses | 56 |
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| Kelechi Iheanacho | 76 |
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| Kelechi Iheanacho for Odion Ighalo | 61 |
| Mikel Agu for John Obi Mikel | 69 |
| Ahmed Musa for Victor Moses | 83 |
| Odion Ighalo | 30 | Y |
Manager: Hugo Broos
| Eric Maxim Choupo-Moting for Moumi Ngamaleu | 46 |
| Arnaud Djoum for Eric Maxim Choupo-Moting | 59 |
| Fabrice Olinga for Christian Bassogog | 85 |
| Michael Ngadeu | 23 | Y |
| Adolphe Teikeu | 26 | Y |