| Score | 4-1 to Preston North End |
| Referee | Lee Probert |
| Competition | FA Cup 4th round |
| Venue | Pride Park |
| Attendance | 17,344 |
View Derby County v Preston North End head to head
| Robert Earnshaw | 55 |
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| Gary Teale for Eddie Lewis | 24 |
| Giles Barnes for Andy Todd | 46 |
| Robert Earnshaw for Emanuel Villa | 46 |
| Stephen Pearson | 67 | Y |
| Lewin Nyatanga | 90 | R |
| Karl Hawley | 14 |
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| Simon Whaley | 33 |
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| Karl Hawley | 45 |
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| Neil Mellor | penalty | 90 |
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| Matt Hill for Callum Davidson | 46 |
| Neil Mellor for Karl Hawley | 85 |
| Kevin Nicholls for Simon Whaley | 86 |
| Chris Sedgwick | 71 | Y |
Comments:
Unused substitutes: Ben Hinchliffe and Dean LeacockComments:
Unused substitutes: Chris Neal and Brett Ormerod