| Score | 2-0 to Spain |
| Referee | Nikola Dabanović |
| Competition | UEFA Nations League League A Group A3 |
| Venue | epet ARENA, Prague |
| Attendance | 18,193 |
View Czech Republic v Spain head to head
Manager: Santiago Denia Sanchez
| Idris Hopi for Ryan Naderi | 66 |
| Martin Subert for Lukáš Provod | 66 |
| Tomáš Vlček for Lukáš Ambros | 76 |
| Christophe Kabongo for Adam Hložek | 84 |
| Tomáš Souček for Lukáš Cerv | 84 |
| Ladislav Krejčí | 69 | R |
Manager: Luis De La Fuente
| Alex Baena | penalty | 39 |
|
| Marc Pubill | 90+6 |
|
| Mikel Merino for Yeremy Pino | 66 |
| Roberto Fernández for Ferran Torres | 66 |
| Pedri for Fabián Ruiz | 76 |
| Marc Pubill for Pedro Porro | 76 |
| Jorge de Frutos for Fermín López | 82 |
| Pedro Porro | 11 | Y |
| Mikel Merino | 69 | Y |