Zenit St Petersburg v Villarreal, 07 March 2019
| Score | 3-1 to Villarreal |
| Referee | Gianluca Rocchi |
| Competition | UEFA Europa League Round of 16 1st leg |
| Venue | Gazprom Arena, Saint Petersburg |
| Attendance | 51,826 |
Kick-off: 8.55pm local (5.55pm GMT)
1 Zenit St Petersburg
Manager: Sergey Semak
3 Villarreal
Manager: Javier Calleja