Young Boys Berne v Villarreal, 20 October 2021
| Score | 4-1 to Villarreal |
| Referee | Sergei Karasev |
| Competition | UEFA Champions League Group F |
| Venue | Stadion Wankdorf, Berne |
| Attendance | 27,398 |
Kick-off: 9.00pm local
1 Young Boys Berne
Manager: David Wagner
4 Villarreal
Manager: Unai Emery