Wigan Athletic v Southampton, 18 March 2018
| Score | 2-0 to Southampton |
| Referee | Michael Oliver |
| Competition | FA Cup Quarter-final |
| Venue | DW Stadium |
| Attendance | 17,110 |
View Wigan Athletic v Southampton head to head
Kick-off: 1.30pm
Goals:
Starting lineup:
Goalkeeper
Christian Walton
Defender
Dan Burn
Defender
Nathan Byrne
Defender
Chey Dunkley
Defender
Callum Elder
Midfielder
Michael Jacobs
Midfielder
Sam Morsy
Midfielder
Max Power
Midfielder
Gary M Roberts
Forward
Will Grigg
Forward
Gavin Massey
Substitutions:
| Ryan Colclough for Gary M Roberts | 66 |
| Nick Powell for Gavin Massey | 66 |
| Noel Hunt for Nathan Byrne | 80 |
Cards:
| Dan Burn | 72 | Y |
| Chey Dunkley | 85 | Y |
On the bench:
Goalkeeper
Jamie Jones
Defender
Alex Bruce
Midfielder
Jay Fulton
Midfielder
David Perkins
Midfielder/Forward
Ryan Colclough
Midfielder/Forward
Nick Powell
Forward
Noel Hunt
Goals:
| Pierre-Emile Hojbjerg | 62 |
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| Cédric Soares | 90 |
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Starting lineup:
Alex McCarthy
Goalkeeper
Cédric Soares
Defender
Wesley Hoedt
Defender
Jack Stephens
Defender
Ryan Bertrand
Defender/Midfielder
Mario Lemina
Defender/Midfielder
Pierre-Emile Hojbjerg
Midfielder
Sofiane Boufal
Midfielder/Forward
Dušan Tadić
Midfielder/Forward
Guido Carrillo
Forward
Manolo Gabbiadini
Forward
Substitutions:
| Nathan Redmond for Sofiane Boufal | 65 |
| Shane Long for Guido Carrillo | 81 |
| Oriol Romeu for Manolo Gabbiadini | 87 |
Cards:
On the bench:
Goalkeeper
Fraser Forster
Defender
Maya Yoshida
Midfielder
Josh Sims
Midfielder
James Ward-Prowse
Midfielder/Forward
Nathan Redmond
Midfielder/Forward
Oriol Romeu
Forward
Manolo Gabbiadini
Forward
Shane Long