Villarreal v Bayer Leverkusen, 10 March 2016
| Score | 2-0 to Villarreal |
| Referee | Gianluca Rocchi |
| Competition | UEFA Europa League Round of 16 1st leg |
| Venue | Estadio El Madrigal, Villarreal |
| Attendance | 16,211 |
Kick-off: 9.05pm local (8.05pm GMT)
2 Villarreal
Manager: Marcelino
Goals:
| Cédric Bakambu | 4 |
|
|
| Cédric Bakambu | 56 |
|
Starting lineup:
Goalkeeper
Alphonse Areola
Defender
Eric Bailly
Defender
Mario
Defender
Victor Ruiz
Defender
Antonio Rukavina
Midfielder
Bruno Soriano
(captain)
Midfielder
Denis Suárez
Midfielder
Manu Trigueros
Forward
Cédric Bakambu
Forward
Samu Castillejo
Forward
Soldado
Substitutions:
| Leo Baptistao for Soldado | 76 |
| Nahuel for Samu Castillejo | 80 |
| Adrian Lopez for Cédric Bakambu | 82 |
Cards:
| Manu Trigueros | 72 | Y |
On the bench:
Goalkeeper
Sergio Asenjo
Defender
Daniele Bonera
Defender
Adrian Marin
Midfielder
Tomas Pina
Forward
Adrian Lopez
Forward
Leo Baptistao
Forward
Nahuel
0 Bayer Leverkusen
Manager: Roger Schmidt
Goals:
Starting lineup:
Bernd Leno
Goalkeeper
Tin Jedvaj
Defender
Kyriakos Papadopoulos
Defender
Jonathan Tah
Defender
Wendell
Defender
Karim Bellarabi
Midfielder
Julian Brandt
Midfielder
Hakan Çalhanoğlu
Midfielder
(captain)
Christoph Kramer
Midfielder
Javier Hernández
Forward
Stefan Kiessling
Forward
Substitutions:
| Marlon Frey for Christoph Kramer | 65 |
| Robbie Kruse for Stefan Kiessling | 67 |
| Admir Mehmedi for Karim Bellarabi | 86 |
Cards:
| Jonathan Tah | 14 | Y |
| Javier Hernández | 48 | Y |
| Tin Jedvaj | 76 | Y |
| Tin Jedvaj | 90 | Y |
| Tin Jedvaj | 90 | R |
On the bench:
Goalkeeper
Dario Kresic
Defender
Andre Ramalho
Defender/Midfielder
Benjamin Henrichs
Midfielder
Marlon Frey
Midfielder
Vladlen Yurchenko
Midfielder/Forward
Robbie Kruse
Forward
Admir Mehmedi