Villarreal v Anderlecht, 16 March 2023
| Score | 1-0 to Anderlecht |
| Referee | Marco Di Bello |
| Competition | UEFA Europa Conference League Round of 16 2nd leg |
| Venue | Estadi Ciutat de València, València |
| Attendance | 16,212 |
Kick-off: 9.00pm local
.
Anderlecht won 2-1 on aggregate
0 Villarreal
Manager: Quique Setién
1 Anderlecht
Manager: Brian Riemer