Viktoria Plzen v Astra Giurgiu, 20 October 2016
| Score | 2-1 to Astra Giurgiu |
| Referee | Aleksei Eskov |
| Competition | UEFA Europa League Group E |
| Venue | Doosan Arena, Plzeň |
| Attendance | 9,440 |
Kick-off: 9.05pm local
1 Viktoria Plzen
Manager: Roman Pivarnik
2 Astra Giurgiu
Manager: Marius Sumudica