VfL Wolfsburg v Lille OSC, 08 December 2021
| Score | 3-1 to Lille OSC |
| Referee | Daniele Orsato |
| Competition | UEFA Champions League Group G |
| Venue | Volkswagen Arena, Wolfsburg |
| Attendance | 6,544 |
Kick-off: 9.00pm local
1 VfL Wolfsburg
Manager: Florian Kohfeldt
3 Lille OSC
Manager: Jocelyn Gourvennec