Union St Gilloise v Bayer Leverkusen, 20 April 2023
| Score | 4-1 to Bayer Leverkusen |
| Referee | Antonio Mateu Lahoz |
| Competition | UEFA Europa League Quarter-final 2nd leg |
| Venue | Lotto Park, Anderlecht |
| Attendance | 17,069 |
Kick-off: 9.00pm local
.
Bayer Leverkusen won 5-2 on aggregate
1 Union St Gilloise
Manager: Karel Geraerts
4 Bayer Leverkusen
Manager: Xabi Alonso