| Score | 3-1 to Tottenham Hotspur |
| Referee | Stuart Attwell |
| Competition | FA Cup 4th round |
| Venue | Tottenham Hotspur Stadium |
| Attendance | 54,697 |
View Tottenham Hotspur v Brighton and Hove Albion head to head
Manager: Antonio Conte
| Harry Kane | 13 |
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| Solly March | own goal | 24 |
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| Harry Kane | 66 |
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| Dejan Kulusekvski for Lucas Moura | 68 |
| Steven Bergwijn for SON Heung-min | 69 |
| Joe Rodon for Cristian Romero | 77 |
| Rodrigo Bentancur for Harry Winks | 77 |
| Matt Doherty for Emerson Royal | 87 |
| Rodrigo Bentancur | 86 | Y |
Manager: Graham Potter
| Yves Bissouma | 63 |
|
| Joël Veltman for Adam Lallana | 46 |
| Moisés Caicedo for Solly March | 61 |
| Danny Welbeck for Tariq Lamptey | 70 |
| Evan Ferguson for Jakub Moder | 79 |
| Joël Veltman | 57 | Y |