Spartak Trnava v Anderlecht, 20 September 2018
| Score | 1-0 to Spartak Trnava |
| Referee | Kevin Clancy |
| Competition | UEFA Europa League Group D |
| Venue | Štadión Antona Malatinskeho, Trnava |
| Attendance | 17,114 |
Kick-off: 9.00pm local (8.00pm BST)
1 Spartak Trnava
Manager: Radoslav Latal
0 Anderlecht
Manager: Hein Vanhaezebrouck