Sparta Praha v Brondby, 09 December 2021
| Score | 2-0 to Sparta Praha |
| Referee | Craig Pawson |
| Competition | UEFA Europa League Group A |
| Venue | Stadion Letná, Prague |
| Attendance | 976 |
Kick-off: 6.45pm local
2 Sparta Praha
Manager: Pavel Vrba
0 Brondby
Manager: Niels Frederiksen