Southampton v Arsenal, 28 January 2017
| Score | 5-0 to Arsenal |
| Referee | Kevin Friend |
| Competition | FA Cup 4th round |
| Venue | St Mary's Stadium, Southampton |
| Attendance | 31,288 |
View Southampton v Arsenal head to head
Kick-off: 5.30pm
Goals:
Starting lineup:
Goalkeeper
Harry Lewis
Defender
Florin Gardoș
Defender
Cuco Martina
Defender
Jack Stephens
Defender/Midfielder
Sam McQueen
Defender/Midfielder
Harrison Reed
Midfielder
Jordy Clasie
Midfielder
Pierre-Emile Højbjerg
Midfielder
Lloyd Isgrove
Midfielder
Josh Sims
Forward
Shane Long
Substitutions:
| Dušan Tadić for Lloyd Isgrove | 64 |
| Nathan Redmond for Shane Long | 65 |
On the bench:
Goalkeeper
Stuart Taylor
Defender
Maya Yoshida
Defender/Midfielder
Ryan Bertrand
Midfielder
Steven Davis
Midfielder/Forward
Nathan Redmond
Midfielder/Forward
Oriol Romeu
Midfielder/Forward
Dušan Tadić
Comments:
This was Southampton's heaviest home defeat in the FA Cup since they lost 0-5 to Manchester City on 5 February 1910.5 Arsenal
Goals:
| Danny Welbeck | 15 |
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| Danny Welbeck | 22 |
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| Theo Walcott | 35 |
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| Theo Walcott | 69 |
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| Theo Walcott | 84 |
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Starting lineup:
David Ospina
Goalkeeper
Héctor Bellerín
Defender
Rob Holding
Defender
Shkodran Mustafi
Defender
Kieran Gibbs
Defender/Midfielder
Alex Oxlade-Chamberlain
Midfielder
Jeff Reine-Adelaide
Midfielder
Ainsley Maitland-Niles
Midfielder/Forward
Theo Walcott
Midfielder/Forward
Lucas Pérez
Forward
Danny Welbeck
Forward
Substitutions:
| Alexis Sánchez for Danny Welbeck | 65 |
| Alex Iwobi for Jeff Reine-Adelaide | 72 |
On the bench:
Goalkeeper
Emiliano Martínez
Defender
Gabriel Paulista
Defender
Carl Jenkinson
Defender
Per Mertesacker
Defender
Nacho Monreal
Midfielder/Forward
Alex Iwobi
Midfielder/Forward
Alexis Sánchez