Slavia Praha v 1.FC Union Berlin, 16 September 2021
| Score | 3-1 to Slavia Praha |
| Referee | Fabio Verissimo |
| Competition | UEFA Europa Conference League Group E |
| Venue | Sinobo Stadium, Prague |
| Attendance | 15,286 |
Kick-off: 6.45pm local
3 Slavia Praha
Manager: Jindřich Trpišovský
1 1.FC Union Berlin
Manager: Urs Fischer