Sheffield United v Southampton, 21 September 2021
| Score | 2-2 :: penalties 4-2 to Southampton |
| Referee | John Brooks |
| Competition | League Cup 3rd round |
| Venue | Bramall Lane |
| Attendance | 8,934 |
View Sheffield United v Southampton head to head
Kick-off: 7.45pm
Southampton won 4-2 on penalties
Extra time not played
2 (2) Sheffield United
Manager: Slaviša Jokanović
Goals:
Starting lineup:
Substitutions:
Cards:
On the bench:
2 (4) Southampton
Manager: Ralph Hasenhüttl
Goals:
| Ibrahima Diallo | 23 |
|
|
| Mohammed Salisu | 53 |
|
Starting lineup:
Fraser Forster
Goalkeeper
Lyanco
Defender
Mohammed Salisu
Defender
Yann Valery
Defender
Romain Perraud
Defender/Midfielder
Ibrahima Diallo
Midfielder
Nathan Tella
Midfielder
Moussa Djenepo
Midfielder/Forward
Nathan Redmond
Midfielder/Forward
Oriol Romeu
Midfielder/Forward
Armando Broja
Forward
Substitutions:
| James Ward-Prowse for Nathan Redmond | 46 |
| Jan Bednarek for Lyanco | 74 |
| Che Adams for Nathan Tella | 81 |
Cards:
| Lyanco | 33 | Y |
On the bench:
Goalkeeper
Harry Lewis
Defender
Jan Bednarek
Defender/Midfielder
Kyle Walker-Peters
Midfielder
James Ward-Prowse
Midfielder/Forward
Che Adams
Midfielder/Forward
Mohamed Elyounoussi
Forward
Shane Long