Sevilla v Olympique Lyonnais, 27 September 2016
| Score | 1-0 to Sevilla |
| Referee | Bas Nijhuis |
| Competition | UEFA Champions League Group H |
| Venue | Estadio Ramón Sánchez Pizjuán, Sevilla |
| Attendance | 36,741 |
Kick-off: 8.45pm local (7.45pm BST)
1 Sevilla
Manager: Jorge Sampaoli
0 Olympique Lyonnais
Manager: Bruno Génésio