Sao Tome e Principe v Mauritius, 24 March 2022

Kick-off: 4.00pm local Played in Saint Pierre, Mauritius Although Sao Tome e Principe won this game 1-0, an appeal by Mauritius was upheld by the Confederation of African Football (CAF). They were subsequently awarded a 3-0 win on 16 May 2022. As the 2nd leg was played to a 3-3 draw, Sao Tome e Principe were effectively disqualified from the competition due to goalscorer Luís Leal failing to provide a valid COVID-19 test prior to the 1st leg tie. A CAF staement read: "The CAF Disciplinary Board found Sao Tome e Principe Football Federation guilty of fielding an ineligible player for the said match and imposed a forfeit of the match played against Mauritius."