Royal Antwerp v Olympiakos, 09 December 2021
| Score | 1-0 to Royal Antwerp |
| Referee | Marco Di Bello |
| Competition | UEFA Europa League Group D |
| Venue | Bosuilstadion, Antwerp |
| Attendance | 7,992 |
Kick-off: 6.45pm local
1 Royal Antwerp
Manager: Brian Priske
0 Olympiakos
Manager: Pedro Martins