Rio Ave v AC Milan, 01 October 2020
| Score | 2-2 :: penalties 9-8 to AC Milan |
| Referee | Jesús Gil Manzano |
| Competition | UEFA Europa League Play-off |
| Venue | Estádio dos Arcos, Vila do Conde |
Kick-off: 8.00pm local
AC Milan won 9-8 on penalties.
After extra time - 1-1 at 90 minutes.
Due to COVID-19 restrictions, the UEFA Executive Committee decided that all ties played in the Preliminary round, three Qualifying rounds and Play-off round in this season's UEFA Europa League competition should be single-leg matches, hosted by one of the teams decided by draw and played behind closed doors.
2 (8) Rio Ave
Manager: Augusto Gama
2 (9) AC Milan
Manager: Stefano Pioli