Red Bull Salzburg v Lille OSC, 29 September 2021
| Score | 2-1 to Red Bull Salzburg |
| Referee | Halil Umut Meler |
| Competition | UEFA Champions League Group G |
| Venue | Red Bull Arena, Salzburg |
| Attendance | 24,207 |
Kick-off: 9.00pm local
2 Red Bull Salzburg
Manager: Matthias Jaissle
1 Lille OSC
Manager: Jocelyn Gourvennec