Real Betis v Rennes, 21 February 2019
| Score | 3-1 to Rennes |
| Referee | Viktor Kassai |
| Competition | UEFA Europa League Round of 32 2nd leg |
| Venue | Estadio Benito Villamarín, Sevilla |
| Attendance | 43,623 |
Kick-off: 9.00pm local (8.00pm GMT)
Rennes won 6-4 on aggregate
1 Real Betis
Manager: Enrique Setien Solar
3 Rennes
Manager: Julien Stephan