Real Betis v PFC Ludogorets Razgrad, 15 September 2022
| Score | 3-2 to Real Betis |
| Competition | UEFA Europa League Group C |
| Venue | Estadio Benito Villamarín, Sevilla |
| Attendance | 43,113 |
Kick-off: 9.00pm local
| Score | 3-2 to Real Betis |
| Competition | UEFA Europa League Group C |
| Venue | Estadio Benito Villamarín, Sevilla |
| Attendance | 43,113 |