RB Leipzig v Club Brugge, 28 September 2021
| Score | 2-1 to Club Brugge |
| Referee | Slavko Vinčić |
| Competition | UEFA Champions League Group A |
| Venue | Red Bull Arena, Leipzig |
| Attendance | 23,500 |
Kick-off: 9.00pm local
1 RB Leipzig
Manager: Jesse Marsch
2 Club Brugge
Manager: Philippe Clement