RB Leipzig v Atlético Madrid, 13 August 2020
| Score | 2-1 to RB Leipzig |
| Referee | Szymon Marciniak |
| Competition | UEFA Champions League Quarter-final |
| Venue | Estádio José Alvalade, Lisbon |
Kick-off: 8.00pm local
Due to COVID-19 restrictions, the UEFA Executive Committee decided that, from the quarter-finals stage onwards in this season's UEFA Champions League competition, the remaining games should be played as single-leg ties, at a neutral venue in Lisbon, Portugal and behind closed doors.
2 RB Leipzig
Manager: Julian Nagelsmann
1 Atlético Madrid
Manager: Diego Simeone