PSV Eindhoven v Omonia Nicosia, 10 December 2020
| Score | 4-0 to PSV Eindhoven |
| Referee | Kevin Clancy |
| Competition | UEFA Europa League Group E |
| Venue | Philips Stadium, Eindhoven |
Kick-off: 6.55pm local
4 PSV Eindhoven
Manager: Roger Schmidt
0 Omonia Nicosia
Manager: Henning Berg