PSV Eindhoven v Granada, 22 October 2020
| Score | 2-1 to Granada |
| Referee | Felix Zwayer |
| Competition | UEFA Europa League Group E |
| Venue | Philips Stadium, Eindhoven |
Kick-off: 6.55pm local
Played behind closed doors due to COVID-19 restrictions.
1 PSV Eindhoven
Manager: Roger Schmidt
2 Granada
Manager: Diego Martinez