Olympique Marseille v Lokomotiv Moscow, 09 December 2021
| Score | 1-0 to Olympique Marseille |
| Referee | Willie Collum |
| Competition | UEFA Europa League Group E |
| Venue | Orange Vélodrome, Marseille |
| Attendance | 42,614 |
Kick-off: 9.00pm local
1 Olympique Marseille
Manager: Jorge Sampaoli
0 Lokomotiv Moscow
Manager: Markus Gisdol