Olympique Lyonnais v Brondby, 30 September 2021
| Score | 3-0 to Olympique Lyonnais |
| Referee | Harald Lechner |
| Competition | UEFA Europa League Group A |
| Venue | Groupama Stadium, Lyon |
| Attendance | 25,466 |
Kick-off: 6.45pm local
3 Olympique Lyonnais
Manager: Peter Bosz
0 Brondby
Manager: Niels Frederiksen