Olympiakos v Real Betis, 20 September 2018
| Score | 0-0 |
| Referee | Daniel Stefanski |
| Competition | UEFA Europa League Group F |
| Venue | Stadio Georgios Karaiskaki, Piraeus |
| Attendance | 28,650 |
Kick-off: 10pm local (8.pm BST)
0 Olympiakos
Manager: Pedro Martins
0 Real Betis
Manager: Quique Setién