Olympiakos v Atalanta, 24 February 2022
| Score | 3-0 to Atalanta |
| Referee | Carlos Del Cerro Grande |
| Competition | UEFA Europa League Play-off 2nd leg |
| Venue | Karaiskakis Stadium, Piraeus |
| Attendance | 15,835 |
Kick-off: 7.45pm local
Atalanta won 5-1 on aggregate
0 Olympiakos
Manager: Pedro Martins
3 Atalanta
Manager: Gian Piero Gasperini