Northampton Town v Southampton, 06 October 2020
| Score | 5-0 to Northampton Town |
| Competition | Football League Trophy Group C – South |
| Venue | PTS Academy Stadium |
View Northampton Town v Southampton head to head
Kick-off: 7.45pm
Played behind closed doors due to COVID-19 restrictions.
In line with Premier League and League Championship clubs being allowed to enter the competition, Southampton fielded their Category One Academy team as part of the Elite Player Performance Plan (EPPP) youth development scheme initiated by the Premier League.