Napoli v Villarreal, 25 February 2016
| Score | 1-1 |
| Referee | Deniz Aytekin |
| Competition | UEFA Europa League Round of 32 2nd leg |
| Venue | San Paolo, Naples |
| Attendance | 23,928 |
Villarreal won 2-1 on aggregate.
Kick-off: 9.05pm local (8.05pm GMT)
1 Napoli
Manager: Maurizio Sarri
Goals:
Starting lineup:
Substitutions:
Cards:
On the bench:
1 Villarreal
Manager: Marcelino
Goals:
| Tomas Pina | 59 |
|
Starting lineup:
Alphonse Areola
Goalkeeper
Jaume Costa
Defender
Mario
Defender
Mateo Musacchio
Defender
Victor Ruiz
Defender
Antonio Rukavina
Defender
Bruno Soriano
Midfielder
(captain)
Tomas Pina
Midfielder
Denis Suárez
Midfielder
Cédric Bakambu
Forward
Soldado
Forward
Substitutions:
| Adrian Lopez for Soldado | 71 |
| Samu Castillejo for Antonio Rukavina | 77 |
| Manu Trigueros for Tomas Pina | 84 |
Cards:
| Antonio Rukavina | 25 | Y |
| Bruno Soriano | 36 | Y |
On the bench:
Goalkeeper
Sergio Asenjo
Defender
Eric Bailly
Defender
Daniele Bonera
Midfielder
Manu Trigueros
Forward
Adrian Lopez
Forward
Samu Castillejo
Forward
Leo Baptistao