Napoli v Besiktas, 19 October 2016
| Score | 3-2 to Besiktas |
| Referee | Sergei Karasev |
| Competition | UEFA Champions League Group B |
| Venue | San Paolo, Naples |
| Attendance | 28,502 |
Kick-off: 8.45pm local (7.45pm BST)
2 Napoli
Manager: Maurizio Sarri
3 Besiktas
Manager: Senol Gunes