Middlesbrough v Manchester United, 09 April 1921
| Score | 4-2 to Manchester United |
| Competition | League Division One |
| Venue | Ayresome Park, Middlesbrough |
| Attendance | 15,000 |
View Middlesbrough v Manchester United head to head
James Gallagher made his one and only appearance after moving from Oldham Athletic this year. Moved to Millwall in the summer Wallace Clark made his final appearance before moving to Leeds United in May.
Goals:
| George Carr |
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| George Carr |
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Starting lineup:
Goalkeeper
Tim Williamson
Full back
Walter Holmes
Left back
James Gallagher
Centre half
William Carr
Left half
Peter Donaghy
Left half
Robert Pender
Outside left
Wallace Clark
Outside left
Tom Urwin
Forward
George Carr
Forward
John Carr
Inside right
George Elliott
Goals:
| Joe Spence |
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| Joe Spence |
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| John Grimwood |
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| George Bissett |
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Starting lineup:
John Mew
Goalkeeper
Cyril Barlow
Full back
Charles Moore
Full back
Thomas Forster
Wing half
Clarence Hilditch
Wing half
John Grimwood
Half Back
Fred Hopkin
Outside left
Billy Meredith
Outside right
George Bissett
Forward
Edward Partridge
Forward
Joe Spence
Forward