| Score | 3-0 to Republic of Ireland |
| Referee | Tamás Bognár |
| Competition | FIFA World Cup Europe group A |
| Venue | Stade de Luxembourg, Luxembourg |
| Attendance | 9,268 |
View Luxembourg v Republic of Ireland head to head
Manager: Luc Holtz
| Maurice Deville for Yvandro Borges Sanches | 52 |
| Sébastien Thill for Christopher Martins | 86 |
| Vahid Selimović | 6 | Y |
| Christopher Martins | 19 | Y |
| Maxime Chanot | 77 | Y |
Manager: Stephen Kenny
| Shane Duffy | 67 |
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| Chiedozie Ogbene | 75 |
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| Callum Robinson | 88 |
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| Jason Knight for Adam Idah | 62 |
| Alan Browne for Chiedozie Ogbene | 82 |
| Conor Hourihane for Josh Cullen | 90 |
| Andrew Omobamidele for Callum Robinson | 90 |
| Troy Parrott for Matt Doherty | 90 |
| Josh Cullen | 47 | Y |
| Shane Duffy | 56 | Y |
| Jason Knight | 84 | Y |
| Alan Browne | 90 | Y |