Lokomotiv Moscow v Lazio, 25 November 2021
| Score | 3-0 to Lazio |
| Referee | Artur Dias |
| Competition | UEFA Europa League Group E |
| Venue | RZD Arena, Moscow |
Kick-off: 8.45pm local
0 Lokomotiv Moscow
Manager: Markus Gisdol
3 Lazio
Manager: Maurizio Sarri
| Score | 3-0 to Lazio |
| Referee | Artur Dias |
| Competition | UEFA Europa League Group E |
| Venue | RZD Arena, Moscow |
Manager: Markus Gisdol
Manager: Maurizio Sarri