Lokomotiv Moscow v Galatasaray, 21 October 2021
| Score | 1-0 to Galatasaray |
| Referee | Harald Lechner |
| Competition | UEFA Europa League Group E |
| Venue | RZD Arena, Moscow |
| Attendance | 8,100 |
Kick-off: 10.00pm local
0 Lokomotiv Moscow
Manager: Markus Gisdol
1 Galatasaray
Manager: Fatih Terim