Lille OSC v Sevilla, 20 October 2021
| Score | 0-0 |
| Referee | Michael Oliver |
| Competition | UEFA Champions League Group G |
| Venue | Stade Pierre-Mauroy, Villeneuve D'Ascq |
| Attendance | 34,362 |
Kick-off: 9.00pm local
0 Lille OSC
Manager: Jocelyn Gourvennec
0 Sevilla
Manager: Julen Lopetegui