Lille OSC v Chelsea, 16 March 2022
| Score | 2-1 to Chelsea |
| Referee | Davide Massa |
| Competition | UEFA Champions League Round of 16 2nd leg |
| Venue | Stade Pierre-Mauroy, Villeneuve D'Ascq |
| Attendance | 49,048 |
View Chelsea v Lille OSC head to head
Kick-off: 9.00pm local (8.00pm GMT)
Chelsea won 4-1 on aggregate
1 Lille OSC
Manager: Jocelyn Gourvennec
Goals:
Starting lineup:
Substitutions:
Cards:
On the bench:
2 Chelsea
Manager: Thomas Tuchel
Goals:
| Christian Pulisic | 45 |
|
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| César Azpilicueta | 71 |
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Starting lineup:
Edouard Mendy
Goalkeeper
Andreas Christensen
Defender
Antonio Rüdiger
Defender
Thiago Silva
Defender
César Azpilicueta
Defender/Midfielder
(captain)
Marcos Alonso
Defender/Midfielder
Jorginho
Midfielder
N'Golo Kanté
Midfielder
Mateo Kovačić
Midfielder
Kai Havertz
Midfielder/Forward
Christian Pulisic
Midfielder/Forward
Substitutions:
| Trevoh Chalobah for Andreas Christensen | 33 |
| Mason Mount for Mateo Kovačić | 46 |
| Ruben Loftus-Cheek for Jorginho | 74 |
| Romelu Lukaku for Christian Pulisic | 74 |
| Hakim Ziyech for Kai Havertz | 83 |
Cards:
| Trevoh Chalobah | 34 | Y |
On the bench:
Goalkeeper
Marcus Bettinelli
Goalkeeper
Kepa Arrizabalaga
Defender
Trevoh Chalobah
Defender
Malang Sarr
Defender/Midfielder
Kenedy
Midfielder
Ruben Loftus-Cheek
Midfielder
Mason Mount
Midfielder
Harvey Vale
Midfielder/Forward
Hakim Ziyech
Forward
Romelu Lukaku
Forward
Timo Werner