Leyton Orient v Northampton Town, 23 April 2022
| Score | 4-2 to Northampton Town |
| Competition | League Two |
| Venue | The Breyer Group Stadium |
| Attendance | 6,237 |
View Leyton Orient v Northampton Town head to head
Kick-off: 3.00pm
| Score | 4-2 to Northampton Town |
| Competition | League Two |
| Venue | The Breyer Group Stadium |
| Attendance | 6,237 |
View Leyton Orient v Northampton Town head to head